TL;DR: yes. I’ve had no issues.
Longer …
I’m running a Mac Studio, M1 Max, 64 G ram on Monterey.
In addition to the SonnetTech hub, of which all but one port is in use, I have three USB hubs, one each by HooToo (7 USB A ports and 2 USB A power only ports). Satechi (the under computer model sans SSD drive capability; 3 USB A and 1 USB C ports), and one by Sabrent (4 USB A). I also have three monitors with 2, 2, and 1 USB A ports. All but five of the USB ports are in use.
Only the front two USB C ports on the Studio are not in use. Everything in the back is plugged in.
I have no issues with any of these hubs or the attached peripherals.
I’ve acquired these hubs over time. The HooToo hub I used with my 2010 Mac Pro (after adding a USB 3 card). The Satchi with my 2018 Mini. Two of the monitors are ancient, Apple 20" Cinema Display and 23" Cinema HD!
I have used other hubs that did have issues. Those have been disposed of properly.
The only issue with anything in my set up is that my Magic Trackpad occasionally drops the connection, something that happened much more often with Bluetooth when using the Mac mini. But it usually reconnects after a few seconds.