I think it really depends on your workflow when not at home.
Will an iPad Pro do everything you want comfortably, or require a lot of compromises?
As an indie, I travel mostly for non-work but am always on call for supporting previous projects or handling new clients.
I used to travel with both an iPad Pro and an Intel Macbook. But over time I found myself only using the iPad for content consumption and the Macbook for all work.
When I finally replaced my Intel systems, I chose a Macbook Air. Now I travel only with my MBA and leave the iPad Pro at home (which I still use, but much less).
At home, I use the Macbook Air with an external monitor as a second desk setup. My primary desk is a Mac Studio with external monitor.
For me, keeping two systems in sync has been very easy. All data is synced through iCloud and Dropbox with careful use of ‘selective sync’ as the Macbook Air has 2 TB of storage and the Mac Studio has 4 TB.
I keep a lot of the same apps on both, but not all.
Some apps easily allow using a settings file that can be sync’d using dropbox or icloud, others require manually replicating setting (if desired).
Not fully automatic, but I haven’t found it to be much trouble at all.
P.S. I have found the MacBook Air (M3 version) to be powerful and versatile. If I had only one system, I would definitely be happy with just the MacBook Air for both at home desktop use and grab-and-go travel.
I am thinking of maybe replacing my Mac Studio (original M1 series) in the future and conflicted over getting whatever Mac Mini or Mac Studio is available at that time or consolidating down to a single system using the latest Macbook Air or MacBook Pro.