How to choose a custom shortcut?

So here’s a very basic question - when you set up a new custom shortcut, how do you decide what to use? e.g. how do you know it’s not a really important shortcut for another app? Do you have a system? What are your preferences?


Not very many apps use cmd+ctrl+opt modifiers, and even fewer use shift+cmd+ctrl+opt so those are often safe. In addition there’s KeyCue, which can (usually) tell you which shortcuts are active for a given app.

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