Split Tunneling

I’m not sure that I am using the correct terminology, but my question is whether or not I can have multiple personal vpn devices operating at once. I have Adguard, Microsoft Defender and Freedom all battling for control of my iPad network. Can I have them all running at once?

I certainly have 1Blocker and Surfshark happily running side by side.
But I believe that 1Blocker was specifically written to allow that, not sure on the ones that you have listed.