There are so many variables at play here. Little Snitch’s configuration can be rather complex, and what it does at start up depends on what the Mac is doing at start up, what it is connecting to, etc. Very difficult to diagnose without doing a step-by-step reimplementation of LS. But if you’ve (a) seen faster results without LS, and (b) don’t care if LS is active, then I’d say case closed.
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