I’m using Vuescan with my old Epson Perfection 4870 Photo flatbed scanner and still running ScanSnap with my S510M. I can do a vew quick tests to see if I can run VueScan with the ScanSnap scanner later today and report back.
Edit
Decided it would take only a few minutes so tested it:
VueScan works well with teh scanner, recognized it and all its features upon startup with no problems. However it does not appear to connect to the OCR options at all. Since OCR on the ScanSnap is separate SW I am not surprised. I never use OCR on scanned documents so that wouldn’t bother me but YMMV. I think you can work on getting the OCR to work outside the actual scanning but I don’t know how.